
1
Introduction
1.1 Multifaceted exposure–response relationships
The exposure–response (ER) relationship is a very general concept, since it
may refer to different types of relationships between different types of expo-
sures and their r esponses. This boo k is concerned with modeling quantitative
relationships between drug o r chemical exposures and their response s, with an
emphasis on modeling ER relationships in the pharmac eutical environment.
However, the approaches described in this book are readily applicable to a
wider range of topics such as environmetric modeling and area s in biostatis-
tics where the source of exposure is not drugs or chemicals. ...