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Exposure-Response Modeling
book

Exposure-Response Modeling

by Jixian Wang
July 2015
Intermediate to advanced content levelIntermediate to advanced
351 pages
10h 2m
English
Chapman and Hall/CRC
Content preview from Exposure-Response Modeling
150 Exposure-Response Modeling: Methods and Practical Implementation
where h
0kk
(t) is the specific baseline risk for tr ansition between the two states.
Then, given function c(t), the transition time can be generated accordingly.
Other state depe ndent covariates can be added without additional difficulties.
One special issue is whether one should restart the clock for h
0kk
(t), i.e., use
h
0kk
(t t
k
) where t
k
is the time of reaching state k. However, this is a model
sp ecification issue rather than a simulation issue, as the approaches stated
here c an cope with bo th situations.
The following algorithm generates recurrent events fro m a two-state (event
“on” and “off”) model for piecewise constant exposure within time intervals
t
j
, t
j+1
, j = 1, ...,
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Publisher Resources

ISBN: 9781466573215