
Contents
Preface ix
Epigraph xiii
1 Introduction 1
1.1 What is feedback control? . . . . . . . . . . . . . . . . . . . . 1
1.2 Feedback control in biological systems . . . . . . . . . . . . . 4
1.2.1 The tryptophan operon feedback control system . . . . 5
1.2.2 The polyamine feedback control system . . . . . . . . 6
1.2.3 The heat shock feedback control system . . . . . . . . 7
1.3 Application of control theory to biologica l systems: A histor-
ical perspective . . . . . . . . . . . . . . . . . . . . . . . . . . 10
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2 Linear systems 17
2.1 Introduction . . . . . . . . . . . .