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Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
6 Feedback Control in Systems Biology
C
1
C
2
C
3
P
1
P
2
P
3
Tryptophan
-
-
-
+
+
FIGURE 1.5: Tryptopha n operon regula tory sy stem in E. coli viewed as a dis-
tributed feedback control system: tryptophan is the product of three processes
in series, namely transcription P
1
, translation P
2
and tryptophan synthesis
P
3
, controlled by three distinct negative feedback controllers, namely genetic
regulation C
1
, mRNA attenuation C
2
and enzyme inhibition C
3
.
1.2.2 The polyamine feedback control system
Polyamines are esse ntial, ubiquitous polycations found in all eukaryotic and
most prokaryotic cells. They are utilised in a wide range of core cellular
processes such as binding ...
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Publisher Resources

ISBN: 9781439816912