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Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
Positive feedback systems 171
TABLE 5.1
Parameters for model (5.15). The values have been chosen in [5 ]
such that the model kinetics a re consistent with experimentally
available data
Parameter Value Unit Parameter Value Unit
MEK
tot
1200 nM p42
tot
300 nM
V
0
0.0015 s
1
· nM
1
V
1
2e06 s
1
V
2
1.2 nM · s
1
K
2
200 nM
V
2
1.2 nM · s
1
K
2
200 nM
V
3
0.064 s
1
K
3
1200 nM
V
4
0.064 s
1
K
4
1200 nM
V
5
5 nM · s
1
K
5
1200 nM
V
6
5 nM · s
1
K
6
1200 nM
V
7
0.06 s
1
K
7
300 nM
V
8
0.06 s
1
K
8
300 nM
V
9
5 nM · s
1
K
9
300 nM
V
10
5 nM · s
1
K
10
300 nM
Recall from Section 5.3 that, for each of the three modules, we have to verify
that (A) the op en-loop subsystem has a monostable steady-state response to
constant inputs ...
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Publisher Resources

ISBN: 9781439816912