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Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
6
Model validation using robustness analysis
6.1 Introduction
Robustness, the ability of a system to function correctly in the presence of
both internal and external uncertainty, has emer ged as a key organising prin-
ciple in many biological sys tems . Biological robustnes s has thus become a
major focus of research in systems biology, particularly on the engineering–
biology interface, since the concept of robustness was first rigorously defined
in the context of engineering control systems. This chapter focuses o n one
particularly important aspect of robustness in systems biology, i.e. the use
of ro bus tness analysis methods for the validation or
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Publisher Resources

ISBN: 9781439816912