Skip to Main Content
Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
190 Feedback Control in Systems Biology
that hierarchical control might be important for achieving robustness. The
complex feedback structures encountered in vivo were shown to confer robust
precision and adjustability of the clock while avoiding catastrophic failure.
Two recent papers have proposed effective strategies for overcoming the
local, one-parameter-at-a-time limitations of traditional sensitiv ity analysis.
In [23], the authors used sensitivity analysis to validate a new computational
model of signal transducer and activator of transcription-3 (Stat3) pathway
kinetics, a signaling network involved in e mbryonic stem cell self-renewal.
Transient pathway behaviour was simulated for a 40-fold range of values for
each model parameter in order ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

Mathematical Models for Society and Biology, 2nd Edition

Mathematical Models for Society and Biology, 2nd Edition

Edward Beltrami

Publisher Resources

ISBN: 9781439816912