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Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
7
Reverse engineering biomolecular networks
7.1 Introduction
Fundamental breakthroughs in the field of biotechnology over the last decade,
such a s cDNA microarrays and oligonucleotide chips, [1 , 2], have made high-
throughput and quantitative experimental measurements of biological systems
much easier and cheaper to make. The availability of such an overwhelming
amount of data, however, poses a new challenge for modellers: how to reverse
engineer biological systems at the molecular level using their measured re-
sponses to external pertur bations (e.g. drugs, signalling mole cules, pathogens)
and changes in environmental conditions (e.g. change in
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Publisher Resources

ISBN: 9781439816912