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Feedback Control in Systems Biology
book

Feedback Control in Systems Biology

by Carlo Cosentino, Declan Bates
October 2011
Intermediate to advanced content levelIntermediate to advanced
296 pages
9h 39m
English
CRC Press
Content preview from Feedback Control in Systems Biology
Reverse engineering biomolecular networks 221
(3,1) (1,2) (3,2) (4,2) (1,4) (2,4) (2,1) (4,1) (1,3) (2,3) (4,3) (3,4)
0
0.2
0.4
0.6
0.8
1
Parameter estimates (noise σ=0.05)
(3,1) (1,2) (3,2) (4,2) (1,4) (2,4) (2,1) (4,1) (1,3) (2,3) (4,3) (3,4)
0
0.2
0.4
0.6
0.8
1
Normalised valueNormalised value
Parameter estimates (noise σ=0.3)
FIGURE 7.4: Distribution o f the normalised va lues of the optimised param-
eters over 100 experiments for two different noise levels (Example 7.2). The
first six box plots from the left are those corresponding to the actually existing
edges of the original network; the second six are incorrect predictions (la bels
on the x-axis denote the ...
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Publisher Resources

ISBN: 9781439816912