8.3. The biochemistry of lipid accumulation in the oleaginous microorganisms
8.3.1. General remarks
When various sugars or similarly metabolized compounds (eg, glycerol, polysaccharides) are utilized for the production of SCO, accumulation of lipid in the microbial cells or mycelia (the so-called “de novo” lipid accumulation process) is triggered by exhaustion of nitrogen from the growth medium, which allows the conversion of sugar to storage lipid (Ratledge, 1988, 1994; Ratledge and Wynn, 2002; Wynn and Ratledge, 2006; Papanikolaou and Aggelis, 2009, 2011; Fakas et al., 2009b). In contrast, when growth is conducted on hydrophobic carbon sources (eg, fats, oils), accumulation of storage lipids (the so-called “ex novo” lipid accumulation process) ...
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