July 2018
Beginner to intermediate
376 pages
9h 1m
English
The primary biliary cirrhosis data was introduced in first two chapters using the jackknife method. Observations in clinical trials are usually subject to censoring, and the jackknife method helps to complete incomplete observations through the idea of pseudo values. Since pseudo values are likely to be dependent on each other, the generalized estimating equation framework made it possible to estimate the impact of twelve covariates at the time of interest. The idea of pseudo values and the generalized estimating equation framework makes it easy for practitioners to interpret the results. However, this method might not be useful if the number of censored observations is exceptionally high. Furthermore, it ...