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Hydroxyapatite by Yoshiki Oshida

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CHAPTER 6

BONE-GRAFT SUBSTITUTE MATERIALS

Yoshiki Oshida and Kyo’ichiro Imai

6.1   INTRODUCTION

Bone, a natural composite, comprises nonstoichiometric calcium hydroxyapatite (HA) precipitated in a controlled reaction environment of a highly aligned, anisotropic organic template (type I collagen) that leads to its exotic tensile and compressive strength [1]. Bone plays an important role in the movement, support, and protection of vital organs. It is a composite comprising an organic phase (embedded in strong yet soft protein collagen) by which calcium containing inorganic hard and brittle mineral apatite crystals are embedded [2]. Specifically, bone is a natural composite material, which by weight contains about 60 percent mineral, 30 percent ...

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