Introduction
The biological life sciences have undergone a revolution in studies ranging from single-gene or simplistic disease mechanisms to large scale and complex systems-based molecular studies. This change has been driven by advances in genome sequencing throughput and lowered costs. The broad adoption of high-throughput genome sequencing has accelerated the pace of discovery of the causal mechanisms of diseases. However, the new pace has created very large amounts of data that has overwhelmed the ability of scientists and engineers who are ...

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