
Immune System Modelling and Simulation
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the virtual mouse has become three: one sports active attrition,
one has passive attrition, one—probably the most realistic—has
both varieties together. All the rest in them is identical, and easy
to compare, in the total openness of their immune system as
simulated by IMMSIM (see Figure 16).
Figure 16. Mathematical modeling of memory T-cell attrition, demonstrating active,
passive, or both mechanisms: Tc memory clone dynamics during the primary and
secondary response to cross-reacting viruses, under three scenarios of attrition
simulated by IMMSIM. Abscissa: time steps. Ordinate: Tc memory clone cell counts. ...