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Immune System Modelling and Simulation
book

Immune System Modelling and Simulation

by Filippo Castiglione, Franco Celada
April 2015
Intermediate to advanced content levelIntermediate to advanced
286 pages
7h 23m
English
CRC Press
Content preview from Immune System Modelling and Simulation
Immune System Modelling and Simulation
116
3.1 Model Compartments
C-ImmSim is composed of three modules or compartments
that correspond to three different and separate anatomical
regions of mammals (see Figure 24): (i) the bone marrow where
the haematopoietic stem cell is simulated by producing new
lymphoid and myeloid cells; (ii) the thymus gland where T
lymphocytes are selected to avoid auto-reactivity; and (iii) a
tertiary organ like a lymph node.
In C-ImmSim, the space is discretised and a single lymph
node of a vertebrate animal is mapped onto a two-dimensional
hexagonal (or triangular) lattice, with periodic boundary
conditions (Figure 25). ...
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Publisher Resources

ISBN: 9781466597488