
Immune System Modelling and Simulation
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DUPLICATING. After completion of the duplication phase,
these cells return to the ACTIVE state. Note that, once activated,
the helper T-cell does not go back to the RESTING or ANERGIC
state but remains committed to be active or duplicating, unless
it interacts with a T regulatory specifi c cell.
The model includes two subclasses of helpers: Th1 and
Th2. The same stochastic fi nite state machine, as in Figure 28,
can describe their behaviour. Regulatory T-cells can be as well
illustrated by this SFSM with the only difference that they are
inhibited by nothing.
F igure 28. T helper cells start in the RESTING ...