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Immune System Modelling and Simulation
book

Immune System Modelling and Simulation

by Filippo Castiglione, Franco Celada
April 2015
Intermediate to advanced content levelIntermediate to advanced
286 pages
7h 23m
English
CRC Press
Content preview from Immune System Modelling and Simulation
131
‘complex’ molecules like immunoglobulins that need to be
represented with a binary string.
In nature, immunoglobulins are divided into fi ve different
classes based on differences in the amino acid sequence in the
constant region of the heavy chains [101]. All immunoglobulins
within a given class will have very similar heavy chain constant
regions: IgG-γ, IgM-µ, IgA-α, IgD-δ and IgE-ε heavy chains.
In general, however, IgG is prominent and the most versatile
immunoglobulin, capable of carrying out all the functions of
immunoglobulins. For the purpose of simulating its effect in a
virtual immune system, suffi ce it to say that IgG is the major
immunoglobulin in serum (75% of serum antibodies) and the
major immunoglobulin in extra vascular spaces. ...
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Publisher Resources

ISBN: 9781466597488