Skip to Main Content
Immune System Modelling and Simulation
book

Immune System Modelling and Simulation

by Filippo Castiglione, Franco Celada
April 2015
Intermediate to advanced content levelIntermediate to advanced
286 pages
7h 23m
English
CRC Press
Content preview from Immune System Modelling and Simulation
Immune System Modelling and Simulation
182
4.2 Exhaustion
The dose of the injected antigen plays a non-trivial role in
determining isotype switches, Th polarisation, and so on.
Moreover, while low dosages are not able to elicit a long-lasting
memory, a high dose can make the system (i.e., cell population
compartment) hit some constraints. This results in a kind of
systemic saturation with consequential delay in clearing the
antigen. This feature has been investigated by performing a
study in which increasing dosages of antigen have been injected
to the system in a single shot, and the total antibodies measured
at population peak. The result is ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

Social-Behavioral Modeling for Complex Systems

Social-Behavioral Modeling for Complex Systems

Paul K. Davis, Angela O'Mahony, Jonathan Pfautz
Bioinformatics and Medical Applications

Bioinformatics and Medical Applications

A. Suresh, S. Vimal, Y. Harold Robinson, Dhinesh Kumar Ramaswami, R. Udendhran

Publisher Resources

ISBN: 9781466597488