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Immune System Modelling and Simulation
book

Immune System Modelling and Simulation

by Filippo Castiglione, Franco Celada
April 2015
Intermediate to advanced content levelIntermediate to advanced
286 pages
7h 23m
English
CRC Press
Content preview from Immune System Modelling and Simulation
Immune System Modelling and Simulation
202
With respect to other known diseases caused by viruses, the
natural history of HIV infection and the onset of AIDS shows
a singular time evolution that has particularly stimulated
mathematicians [130]: (i) the fi rst contact with the virus induces
a normal primary immune response, very similar to any other
infection, which lasts no more than a couple of months; (ii) this
acute phase is followed by a period of latency (from two to
eight years) during which the HIV plays ‘hide-and-seek’ with
the immune system; (iii) when the CD4 T-cell count drops to
about 20% of the normal value (around 10
3
cells per ml), there
is the onset of a highly immunodefi cient status. At this time,
the immune system becomes unable ...
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Publisher Resources

ISBN: 9781466597488