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Immune System Modelling and Simulation
book

Immune System Modelling and Simulation

by Filippo Castiglione, Franco Celada
April 2015
Intermediate to advanced content levelIntermediate to advanced
286 pages
7h 23m
English
CRC Press
Content preview from Immune System Modelling and Simulation
Immune System Modelling and Simulation
248
Figure 15. Left panel: The humoral response. Starting from the top and proceeding
counter clockwise, the virus enters an epithelial cell Ep and begins to multiply. In
succession, Ep displays part of the virus (V) on its MHC class-1 then lyses, liberating
virus particles. Some of these are picked up by a resting macrophage or dendritic
cell (Dc), which also perceives a damage or danger signal. Thus, it transits to an
aroused state (light blue shaded Dc), and moves towards a regional lymph node.
Here it displays a viral peptide on its class-1 MHC molecule, and if a virgin Th2 makes
speci c contact, it ...
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Publisher Resources

ISBN: 9781466597488