In Silico Bees

7 QSAR Modeling of Pesticide Toxicity to Bees

James Devillers

CONTENTS

Abstract

Keywords

7.1 Introduction

7.2 What Is a QSAR Model?

7.3 Congeneric QSAR Models on Bees

7.4 Noncongeneric QSAR Models on Bees

7.5 Advantages and Limitations of QSAR Models for Predicting the Toxicity of Chemicals to Bees

References

ABSTRACT

Quantitative structure–activity relationship (QSAR) models are increasingly used in toxicology, ecotoxicology, and pharmacology for predicting the activity of organic molecules from their physicochemical properties and/or their structural characteristics. The available congeneric and noncongeneric QSAR models used to estimate the acute toxicity of pesticides to honey bees were critically analyzed. From ...