Information Technology and Computer Application Engineering – Liu, Sung & Yao (Eds)
© 2014 Taylor & Francis Group, London, ISBN 978-1-138-00079-7
Study on the radiosensitivity of AT cells with HPRT gene mutation
J. Liu, K.J. Dai, C.H. Zheng & L. Chen
Changzhou Tumor Hospital, Soochow University, Changzhou
Z.H. Lu & X.F. Zhou
Dongping People Hospital, Taian
ABSTRACT: It is to investigate the high radiosensitivity of fibroblast cell lines AT5BIVA (AT cells) from the
skin of the patients with ataxia-telangiectasia (AT). With the fibroblast cell lines GM0639 (GM cells) as control,
hypoxanthine phospho-ribosyltransferase (hprt) locus mutation analysis and Cytokinesis-Block micronucleus
method (CBMN) are employed. After AT cells and GM cells were irradiated ...