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It Takes a Genome: How a Clash Between Our Genes and Modern Life Is Making Us Sick by Greg Gibson

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Chapter 8

height and weight

The first phase genome scan for height was published by M. Weedon et al. (2007) Nature Genetics 39: 1245-1250 “A common variant of HMGA2 is associated with adult and childhood height in the general population.” A follow-up has been submitted, while a second group presented S. Sanna et al. (2008) Nature Genetics 40: 198-203 “Common variants in the GDF5-UQCC region are associated with variation in human height.”

Canine size is described in N. B. Sutter et al. (2007) Science 316: 112-115 “A single IGF1 allele is a major determinant of small size in dogs.” Spady, T. C. and E. A. Ostrander (2008) American Journal of Human Genetics 82: 10-18 “Canine behavioral genetics: pointing out the phenotypes and herding up the genes” ...

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