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JMP 11 Design of Experiments Guide by SAS Institute

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Definitive Screening Platform Overview
With traditional screening designs, correlated main effects and confounded two-factor interactions often lead to costly follow-up runs. Definitive screening provides a way to avoid model ambiguity due to confounding and identify important factors more quickly.
Definitive screening designs offer the following advantages:
For continuous factors, the number of required runs is only one more than twice the number of factors. Categorical factors require two more than twice the number of factors.
Unlike resolution III designs, main effects are completely independent of two-factor interactions. As a result, estimates of main effects are not biased by the presence of active two-factor interactions, regardless ...

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