Excel gives you a great deal of flexibility in how you lay out your worksheets. Each worksheet contains more than 16 billion cells, and you can put pretty much as many worksheets in a workbook as you want.
NOTE: If you pack a huge number of worksheets into a workbook and populate them all with data, you may find that Excel slows your Mac down. If this happens, move some of the worksheets into another workbook to improve performance.
Here are four rules to follow when laying out your worksheets to make them as easy as possible to use.