In Neo4j, indexes are used to find the starting points of the queries. You can count on them. Indexes are automatically created on properties that have a constraint. Otherwise, you can create an index with a query like the following:
CREATE INDEX ON :LabelName(propertyName)
However, refrain from creating an index for every property of each label as they need to be maintained by the server when data is inserted. It is taken care of here, but there is no magic.
The command to get the list of indexes in use in your graph is as follows: