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Machine Learning for Protein Subcellular Localization Prediction by Man-Wai Mak, Shibiao Wan

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1 Introduction

Protein subcellular localization is one of the most essential and indispensable topics in proteomics research. Recent years have witnessed the incredibly fast development of molecular biology and computer science, making it possible to utilize computational methods to determine the subcellular locations of proteins. This chapter introduces the background knowledge about proteins, their subcellular locations, and the significance of protein subcellular localization prediction.

1.1 Proteins and their subcellular locations

Proteins, which are essential biological macromolecules for organisms, consist of one or more chains of amino acids residues which are encoded by genes. Proteins occur in a great variety and exist in all cells and ...

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