Chapter 18Mechanobiology
Jun Nakanishi
MANA, National Institute for Material Sciences, 1-1 Namiki, Tsukuba-Shi, Ibaraki, 305-0044, Japan
18.1 Introduction
Subsequent to the first report on the double helical structures of DNA by James Watson and Francis Click in 1953, molecular biology became the center of life science research and continues to maintain this positioning. On the other hand, recent studies demonstrated the involvement of physical force in the regulation of diverse biological reactions. This fact evoked a new discipline, “mechanobiology,” arousing the academic curiosity of researchers of various fields [1–3]. Molecular biologists sought for and successfully identified proteins that translate mechanical stimuli to biological ...
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