Default Gateways and Routing
Another point of confusion when configuring the network adapters is where to place the default gateway.
A rule of thumb to follow is that a server can have only one default gateway. This means that no matter how many network adapters a server has, only one of those should have a default gateway.
Many administrators try to place gateways on both network adapters, which causes extremely unreliable traffic flows. It does not matter if the adapters are all on the same or different subnets; only one adapter should have a default gateway assigned.
The next decision is where to place the default gateway. For an Edge Server, always place the default gateway on the network adapter associated with the Access Edge Server ...