Microsystems for Bioelectronics

Book description

This book considers physical principles and trends in extremely scaled autonomous microsystems for biomedical applications. It provides a physics-based assessment of the ultimate potential of miniaturization technologies. In particular, fundamental scaling limits for energy sources, sensors, computation and communication subsystems are developed. The book is comprised of seven chapters that examine various facets of semiconductor bioelectronic microsystems. The book targets a broad audience with engineering background and can also be useful for the biomedical community.

Rapid advances in microfabrication technologies are offering new opportunities and capabilities to develop systems for biomedical applications, such as diagnostics and therapy. There is a need for a comprehensive treatment of integrated microsystems comprised of diverse components. In particular is important to understand the scaling limits both for the system and its components. An additional intent is to promote innovative thinking about integrated microsystems.

  • Discusses the diverse components that make up Microsystems
  • Outlines the problems with miniaturization of energy sources
  • Perfect reference for those in both the Engineering and Medical Profession

Table of contents

  1. Front Cover
  2. Microsystems for Bioelectronics
  3. Copyright
  4. Contents
  5. Preface
  6. Acknowledgment
  7. Chapter 1 The nanomorphic cell
    1. 1.1 Introduction
    2. 1.2 Electronic scaling
    3. 1.3 Nanomorphic cell
    4. 1.4 Current status of technologies for autonomous microsystems
    5. 1.5 Concluding remarks
    6. References
  8. Chapter 2 Energy in the small: Integrated micro-scale energy sources
    1. 2.1 Introduction
    2. 2.2 Electrochemical energy: Fundamentals of galvanic cells and supercapacitors (1/3)
    3. 2.2 Electrochemical energy: Fundamentals of galvanic cells and supercapacitors (2/3)
    4. 2.2 Electrochemical energy: Fundamentals of galvanic cells and supercapacitors (3/3)
    5. 2.3 Energy from radioisotopes
    6. 2.4 Remarks on energy harvesting (1/2)
    7. 2.4 Remarks on energy harvesting (2/2)
    8. 2.5 Summary
    9. Appendix: A kinetic model to assess the limits of heat removal
    10. List of symbols
    11. References
  9. Chapter 3 Nanomorphic electronics
    1. 3.1 Introduction
    2. 3.2 Information and information processing
    3. 3.3 Basic physics of binary elements (1/4)
    4. 3.3 Basic physics of binary elements (2/4)
    5. 3.3 Basic physics of binary elements (3/4)
    6. 3.3 Basic physics of binary elements (4/4)
    7. 3.4 System-level analysis (1/3)
    8. 3.4 System-level analysis (2/3)
    9. 3.4 System-level analysis (3/3)
    10. 3.5 Summary
    11. Appendix 1: Quantum confinement
    12. Appendix 2: Derivation of electron travel time (Eq. 3.55)
    13. List of symbols
    14. References
  10. Chapter 4 Sensors at the micro-scale
    1. 4.1 Introduction
    2. 4.2 Sensor basics
    3. 4.3 Analog signal
    4. 4.4 Fundamental sensitivity limit of sensors: Thermal noise
    5. 4.5 What information can be obtained from cells?
    6. 4.6 Sensors of bioelectricity
    7. 4.7 Chemical and biochemical sensors
    8. 4.8 Thermal biosensors (1/2)
    9. 4.8 Thermal biosensors (2/2)
    10. 4.9 Concluding remarks
    11. Glossary of biological terms
    12. List of symbols
    13. References
  11. Chapter 5 Nanomorphic cell communication unit
    1. 5.1 Introduction
    2. 5.2 Electromagnetic radiation
    3. 5.3 Basic RF communication system
    4. 5.4 EM Transducer: A linear antenna
    5. 5.5 Free-space single-photon limit for energy in EM communication
    6. 5.6 Thermal noise limit on communication spectrum
    7. 5.7 The THz communication option (λ ≥ 100 μm)
    8. 5.8 Wireless communication for biomedical applications
    9. 5.9 Optical wavelength communication option λ~1 μm) (1/2)
    10. 5.9 Optical wavelength communication option λ~1 μm) (2/2)
    11. 5.10 Status of μ-scaled LEDs and PDs
    12. 5.11 Concluding remarks
    13. List of symbols
    14. References
  12. Chapter 6 Micron-sized systems: In carbo vs. in silico
    1. 6.1 Introduction
    2. 6.2 Information: A quantitative treatment
    3. 6.3 Abstract information processors
    4. 6.4 In silico and in carbo systems: A design perspective
    5. 6.5 In carbo long-term memory: Storing information in DNA
    6. 6.6 In carbo logic information procession
    7. 6.7 In carbo sensors
    8. 6.8 In carbo communication
    9. 6.9 In carbo energy source
    10. 6.10 Benchmark in carbo information processor
    11. 6.11 Summary
    12. Appendix: Choice of probability values to maximize the entropy function
    13. List of symbols
    14. References
  13. Concluding remarks
  14. Index (1/2)
  15. Index (2/2)

Product information

  • Title: Microsystems for Bioelectronics
  • Author(s): Victor V. Zhirnov, Ralph K. Cavin III
  • Release date: November 2010
  • Publisher(s): Elsevier Science
  • ISBN: 9781437778410