
88 Modeling and In verse Problems in the Presence of Uncertainty
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Histogram Data, t =24 hrs
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Histogram Data, t =48 hrs
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Histogram Data, t =96 hrs
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Histogram Data, t =120 hrs
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FIGURE 3 .10: Typical histogr am data for a CFSE-based proliferation
assay showing cell co unt vs. log fluorescence intensity; originally from [3 0].
The ma thematical modeling problem is to de velop a system of equations
which accounts for the ...