
486 Nanosensors: Physical, Chemical, and Biological
knowledge that exists for the chemical modication of oxide surfaces, e.g.,
from studies of silica and planar chemical sensors.
8.6.2 Functionalization of Si NWs
Two approaches for functionalizing the Si NWs are element-doping and
surface chemical modication (Yang et al. 2006). Compared with the ele-
ment-doping method, chemical modication is easily controlled and able to
anchor various functional groups on the surface of Si NWs. For Si NWs, the
linker molecule of choice depends on whether or not the wire has an oxide
V
DS
V
GS
Biological receptor
Linker
Ligand
S
D
CNT
Silicon dioxide ...