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Nanostructures for Drug Delivery by Alexandru Mihai Grumezescu, Ecaterina Andronescu

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Chapter 2

Core–shell drug carriers: liposomes, polymersomes, and niosomes

Nily Dan    Drexel University, Philadelphia, PA, United States

Abstract

Effective therapies require an efficient method for drug delivery. The main goals of drug delivery systems, or carriers, is to enhance therapeutic efficiency by targeting specific tissue, and to provide control over the rate of drug release. Core–shell vesicle drug carriers are based on bilayer-forming amphiphiles: liposomes composed of phospholipid bilayers, polymersomes composed of copolymers, and niosomes from nonionic surfactants. Designed to carry hydrophilic drugs, they offer, in addition to targeting and controlled release, protection of drugs from degradation, prolonged circulation time in vivo, ...

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