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Nanostructures for Drug Delivery by Alexandru Mihai Grumezescu, Ecaterina Andronescu

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Chapter 8

Brush polymer-based nanostructures for drug delivery

Yun Yu
Haotian Sun
Chong Cheng    University at Buffalo, State University of New York, Buffalo, NY, United States

Abstract

Polymeric nanostructures have been broadly investigated for applications in drug delivery. As compared with other types of polymers, brush polymers (BPs) can possess not only unimolecular but also intermolecularly assembled nanostructures with versatile properties, and therefore drug delivery via BP-based scaffolds has attracted drastically increasing interest. A broad variety of BPs with diverse structural features and properties have been integrated with drugs via either physical encapsulation or chemical conjugation to construct BP-based drug-delivery systems. ...

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