Nanostructures for Drug Delivery

Chapter 13

Nanosuspension drug delivery system: preparation, characterization, postproduction processing, dosage form, and application

Jiuhong Zhang^**

Zhiqiang Xie^†

Nan Zhang^*

Jian Zhong^**    Shanghai Ocean University, Shanghai, People’s Republic of China^**    Kent State University, Kent, OH, United States^†    Louisiana State University, Baton Rouge, LA, United States

Abstract

In the drug research and development field, more and more new drug candidates has been found to be practically insoluble in aqueous solvents and many of them are simultaneously poorly soluble in organic solvents. Since nanosuspension drug delivery system (DDS) was firstly developed in 1994, nanosuspension DDS has attracted more and more attention as a formation solution for ...