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Nanostructures for Drug Delivery by Alexandru Mihai Grumezescu, Ecaterina Andronescu

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Chapter 20

Therapeutic nanostructures for pulmonary drug delivery

Yousef Javadzadeh
Shadi Yaqoubi    Tabriz University of Medical Science, Tabriz, Iran

Abstract

Pulmonary drug delivery has attracted tremendous interest in the past two decades. In order to get both local and systemic effects, lungs as the main part of the respiratory system offer an interesting route to noninvasive drug administration. Inhalation therapy has several advantages over other drug delivery routes; large surface area available in alveolar sacs and high vascularization make the lungs an appropriate site of drug absorption. Advantages of pulmonary drug delivery together with the outstanding attributes of nanoscaled systems, such as (1) reduced size and increased surface ...

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