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Nanostructures for Drug Delivery by Alexandru Mihai Grumezescu, Ecaterina Andronescu

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Chapter 24

Drug delivery mediated by confined nanosystems: structure-activity relations and factors responsible for the efficacy of formulations

Lucia Zakharova
Tatiana Pashirova
Ruslan Kashapov
Dinar Gabdrakhmanov
Oleg Sinyashin    A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russian Federation

Abstract

Herein, nanosized drug delivery systems are reviewed including self-assembled nanocontainers based on amphiphilic compounds (from micelles to liposomes) and polymers (capsules, nanospheres, etc.), with special attention paid to (1) the green chemistry criteria upon the design of carriers, (2) the structure-activity correlations, and (3) binding/release properties. Besides ...

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