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Nanostructures for Drug Delivery by Alexandru Mihai Grumezescu, Ecaterina Andronescu

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Chapter 25

Therapeutic use of monoclonal antibodies: general aspects and challenges for drug delivery

Daniela A. Quinteros*
José M. Bermúdez**
Soledad Ravetti
Alicia Cid**
Daniel A. Allemandi*
Santiago D. Palma**    National University of Salta-CONICET, Salta, Argentina**    National University of Córdoba, Córdoba, Argentina    National University of Villa Maria, Córdoba, Argentina

Abstract

Monoclonal antibodies are routinely used in several fields but the great challenge has been their use as therapeutic agents for the treatment of diseases, such as breast cancer, leukemia, asthma, macular degeneration, arthritis, Crohn’s disease, and transplants, among others.

Monoclonal antibodies are protein molecules made in the laboratory from hybridoma ...

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