Chapter 6

Human Microbiome and Aging

Seema Joshi and Melissa Navinskey,    Dwight D. Eisenhower Veterans Affairs Medical Center, Leavenworth, KS, United States

Abstract

The past decade has seen an increasing interest in the role of the microbiome on human health. Advances in molecular biology have shed light on trillions of microorganisms living in a stable and mutually beneficial relationship with the human host. In addition, there has been increasing evidence that the gut microbiome has an impact on the host immune system. The structure of the gut microbiome appears to be altered by the aging process with an associated increased inflammatory status known as inflammaging that may be predictive of disease. This article discusses recent evidence ...

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