Chapter 15

The Role of B Group Vitamins and Choline in Cognition and Brain Aging

Francesco Bonetti, Gloria Brombo and Giovanni Zuliani,    University of Ferrara, Ferrara, Italy


Brain aging is a balance between homeostatic processes and harmful interactions with the environment. Each individual has a unique aging path. Healthy neurological aging requires maintenance of normal brain functioning and prevention of neuronal damage. Diet is a cornerstone of disease prevention and health promotion. B group vitamins (BGVs) and choline are micronutrients that share a key role in multiple metabolic pathways related to the nervous system’s structural and functional integrity. Almost all BGVs show clinically relevant neurological manifestations in ...

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