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Nutrition and Functional Foods for Healthy Aging by Ronald Ross Watson

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Chapter 22

Calorie Restriction Mimetics From Functional Foods

Impact on Promoting a Healthy Life Span

Wai Yan Sun and Yu Wang,    The University of Hong Kong, Hong Kong, China

Abstract

Aging is a complex process of functional decline at the molecular, cellular, and organ system levels. Even as human life expectancy is being prolonged, age-related diseases continue to be major obstacles for healthy aging and longevity. Evidence from different biological models ranging from yeasts, worms, flies, rodents, and primates to humans suggests a number of conserved aging mechanisms offer pathways to maintain the “youthful” states. Calorie restriction remains the most robust nongenetic approach for extending health and life span. It slows primary aging ...

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