Chapter 18Chemistrode for High Temporal- and Spatial-Resolution Chemical Analysis

Alexander J. Donovan1 and Ying Liu1,2

1University of Illinois at Chicago, Department of Chemical Engineering, Chicago, IL, 60607, USA

2University of Illinois at Chicago, Department of Biopharmaceutical Sciences, Chicago, IL, 60607, USA

18.1 Introduction

The chemistrode is a droplet-based microfluidic device for stimulating, recording, and analyzing molecular signals with high spatiotemporal and chemical resolution. The invention of its electrochemical precursor, the microelectrode, several decades ago allowed for a transformation in the investigation of biophysical phenomena at exquisite fidelity. The pioneers in this new field of electrophysiology, Hodgkin ...

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