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Functionalized microstructured optical fibers for specific nucleic acid detection
A. Candiani, and A. Cucinotta University of Parma, Parma, Italy
Abstract
A new sensing platform for specific DNA strand detection based on microstructured optical fiber Bragg gratings and peptide nucleic acid probes is presented. To achieve optical signal amplification, DNA-functionalized gold nanoparticles are used in a sandwich-like system assay, showing high sensitivity and repeatability of the results. Besides the particular technological approach, we report some practical applications implemented in the medical field and in the food industry.
Keywords
Biosensing; Bragg gratings; DNA detection; Functionalized nanoparticles; Microstructured optical fibers (MOFs) ...Get Optofluidics, Sensors and Actuators in Microstructured Optical Fibers now with the O’Reilly learning platform.
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