8

Plant-Derived Pure Drugs

CHAPTER OBJECTIVES
INTRODUCTION

Up to mid-19th century, the beginning of the era of natural products, plant-derived drugs remained structurally ill-defined. Plant active constituent isolations from crude drugs were successful when the yield was sufficient and the compounds were more amenable to the then available methods of isolations. However such isolations were not possible for most biologically active crude drugs with unstable and/or poor-yield constituents. Also compound characterization required considerable quantities of the isolated constituents. The advent of modern instrumentation and newer techniques in separation ...

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