Chapter 14. Biochemical Engineering[*]

Elementary Step and Approximate Models for Enzyme Kinetics

Concepts Demonstrated

Development of kinetic models for enzymatic reactions occurring in batch reactors and simulation of elementary step and Michaelis-Menten models for batch enzymatic reactors.

Numerical Methods Utilized

Solution of simultaneous ordinary differential equations.

Problem Statement

Simplified models for enzyme-catalyzed reactions are based on reactions that involve reversible adsorption of the enzyme E with a substrate S yielding an enzyme-substrate complex ES. This complex then reacts to yield the enzyme E and the product P. This overall reaction is presented in Equation (14-1).

Equation 14-1. 

Elementary Step Model

The steps in this overall ...

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