Basic principles of multipotent stem cells
A. Kumar and C. Verfaillie, Katholieke Universiteit Leuven Belgium
Abstract:
Since the discovery of hematopoietic stem cells, adult stem cell studies have made significant strides due to their many clinical applications. It is of prime importance to researchers to acquire current knowledge about adult stem cells before they are dispatched for therapeutic use. In this chapter, we discuss the characteristic properties, differentiation ability and clinical applications of various adult-derived adherent stem cells in general and with greater emphasis on multipotent adult progenitor cells (MAPC) which were first isolated in 2002 in our laboratory. MAPCs represent a more primitive phenotype compared ...
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