O'Reilly logo

Purification of Laboratory Chemicals, 8th Edition by W.L.F. Armarego

Stay ahead with the world's most comprehensive technology and business learning platform.

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, tutorials, and more.

Start Free Trial

No credit card required

SIBX is an even more stabilised, non-explosive formulation that has all the oxidative characteristics of IBX. It is prepared as follows: 2-iodobenzoic acid (200g) and isophthalic acid (133g, see [121-91-5]) are added into a solution of oxone (625g) in H2O (2000ml) and kept at 70° for 3 hours, then sodium benzoate (128g) in H2O (500ml) is added at 40°. The precipitate that is formed on cooling to 20° is filtered off, washed with H2O (700ml) and dried in a ventilated oven at 60° to give SBTX (420g, 90%) containing 49% w/w of active IBX. [Ozanne et al. Org Lett 5 2903 2003, DOI: 10.1021/ol0349965.]

SIBX and/or IBX are water tolerant, inexpensive to prepare and easy to use. They oxidise primary and secondary alcohols smoothly to aldehydes and ketones, ...

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, interactive tutorials, and more.

Start Free Trial

No credit card required