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Purification of Laboratory Chemicals, 8th Edition by W.L.F. Armarego

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Proclavine (3,6-diaminoacridine) [92-62-6] C13H11N3, M 209.2, m 284-286°, pK125 -2.7, pK225 0.55, pK325 9.49. It crystallises from aqueous MeOH. The picrate crystallises from aqueous pyridine with m ~ 185°. [Beilstein 22 H 487, 22 I 649, 22 II 397, 22 III/IV 5487, 22/11 V 322, also see Elderfield references above.] For proflavin see 3,6-diaminoacridine hydrochloride.

Propidium iodide (3,8-diamino-5-(3-diethylaminopropyl)-6-phenylphenantridinium iodide methiodide) [25535-16-4] C27H34I2N4, M 668.4, m 210-230°(dec), pKEst(1)~ 4 (aniline NH2), pKEst(2)~ 8.5 (EtN2). It crystallises as red crystals from H2O containing a little KI. It fluoresces strongly and intercalates with nucleic acids; useful in flow cytometry. [Watkins J Chem Soc 3064 1952, DOI: ...

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