The combination of Qt with Python provides flexibility to the Qt developers for developing GUI programs in a more robust language and also providing a rapid application development platform available on all major operating systems. We introduced you to the basics of PySide and its installation procedure on Windows, Linux, and Mac systems. We went on creating our first application which introduced the main components of creating a GUI application and the event loop. We have concluded this chapter with an introduction to exception handling as a best practice. Moving on, we are set to create some real-time applications in PySide.