
28 Sample Size Calculations for Clustered and Longitudinal Outcomes
2.2.2.1 Example
Reports have established the effectiveness of minimally invasive periodontal
surgery (MIPS) in treating osseous defects [12, 13]. Since these papers were
published, new devices (including a videoscope and ultrasonic tips) have been
incorporated to enhance the effectiveness of the procedure. Haffajee et al. [14]
computed the intracluster correlation coefficients of periodontal measurements
for five groups of treated periodontal disease subjects and one group of un-
treated subjects with periodontal disease. The median intracluster correlation
coefficient (ρ) is 0.067 for clinical ...